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Bacterial and viral DNA has a single origin of replication. As a semiconservative process a single molecule containing two strands of DNA in double helix formation is separated where each strand serves as a template for the new DNA molecules. Roles Of Dna Polymerases And Other Replication Enzymes Leading And Lagging Strands And Okazaki Fragments Dna Ligase Dna Replication Dna The detachment of the two single strands of DNA makes a two Y-formed design called a replication fork. . Coli origin oriCDnaA utilizes ATP to destabilize AT-rich repeats within the origin Figure 1a. DNA replication always begins at certain unique and fixed points of DNA called origin. Key Points DNA replication is semiconservative. We may compare the DNA structure to a twisted ladder. The helicase DnaB is a ring-shaped homohexamer 16 17 that. Together they structure a bubble-like design called a replication bubble. It begins at a part

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